Scissors for autolysosome tubules.
نویسندگان
چکیده
Autophagic lysosome reformation (ALR) is a cellular process in which lysosomes are reformed through scission of protolysosomes from tubular structures extruded from autolysosomes. Despite recent progress, the molecular mechanism of ALR is far from clear. A paper in this issue of The EMBO Journal has identified lysosome-localized PI(3)P, which is generated by the VPS34–UVRAG complex in an mTOR-dependent manner, as an important regulator of autolysosome tubule scission (Munson et al, 2015).
منابع مشابه
Lipid droplet breakdown requires Dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes
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Background and aims: Despite automation, still many occupations require the use of hand tools in their routine activities. Scissors are essential tools for many workers in different occupations such as sewing and clothes making.The aim of this study was to investigate the effects of three re-designed models of sewing scissors (models A, B and C) on user performance, tool usability and hand and ...
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[Purpose] The purpose of this study was to research the difference in wrist flexion and accuracy of left-handers when using regular scissors made for right-handed persons versus scissors made for left-handers. [Subjects and Methods] Eighteen left-handers participated in the experiment. There were ten males and eight females subjects. The degree of wrist flexion of 18 left-handers was analyzed w...
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ورودعنوان ژورنال:
- The EMBO journal
دوره 34 17 شماره
صفحات -
تاریخ انتشار 2015